As iridium and the light will help beat cancer
Scientists from the University of Warwick (UK), in collaboration with colleagues from China, France and Switzerland have developed a unique method of cancer therapy. And we are not talking about a new effective drugs. Experts have created a technology that uses light to activate the cancer-killing compounds based on iridium metal. In this method hardly affect normal human cells, thus greatly expands the range of diseases that can resist therapy.
The new method of cancer treatment can save many hundreds of lives
The new method is described in detail in an article published in the edition of Nature Chemistry. At the core of the work it is already quite a long time well-known technology called "photodynamic therapy" (PDT). It uses light to destroy cancer tumors in the body by activating a chemical compound called a photosensitizer. The photosensitizer is good because it is able to "start" only in the presence of a particular wavelength of light. Using this method, physicians can direct the light to specific areas of cancer and prevent damage to normal tissues.
Modern methods of photodynamic therapy mainly rely on the presence of oxygen, but many tumors are "hypoxic", which means that they are experiencing a shortage of oxygen in the surrounding tissues. Therefore, PDT can be used not so often due to poor blood supply. An international team of scientists has now developed iridium-based compound that will kill cancer cells even at low concentrations of oxygen.
All the time in the treatment of cancer, doctors are fighting. Formulations can kill cancer cells, but the re-treatment the cells become resistant, they learn to chemically modify the drug or counteract its action mechanism. Therefore, we need new methods of treatment of neoplastic diseases. - says one of the authors of Professor Peter Sadler. A new method of treatment will cure all of the tumor, where it is possible to use the light. For example, it is suitable for the treatment of bladder cancer, lung, esophagus, brain and skin.
would look like the device for fotodinamichskoy therapy. There are various modifications, but the essence is always the same: light + agent which is activated only in his presence
After light activation, the compound iridium affects the mechanism that is responsible for energy production in cancer cells. The main ingredient in this mechanism is an abbreviation of NADH, but if you're interested in it, "full name" and you want to practice in articulation, please, "nicotinamide". Try to quickly say the word three times in a row, and write in our Telegram channel, whether you have got. But let us not digress, after the destruction of NADH reproduction mechanism, destroyed the whole system of the power of live cancer cells, thereby causing her death. Compound iridium practically does not affect normal cells in the body.
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A team of scientists also noted that to the extent that cancer cells die, they change their structure in such a way that the body begins to recognize their "distinctive features" is known as an immunotherapeutic response. This suggests that those patients who have recovered using this method, can be immunized against the recurrence of the cancer of the same type. That is, people can be protected from relapse.